RGS4 抗体 (AA 1-100)
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Quick Overview for RGS4 抗体 (AA 1-100) (ABIN7269898)
抗原
See all RGS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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原理
- RGS4 Rabbit pAb
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序列
- MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGS4 (NP_005604.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
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别名
- RGS4
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背景
- Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.,RGS4,RGP4,SCZD9,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,Cardiovascular,Heart,Cardiac arrhythmias,Hypertrophy,RGS4
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分子量
- 10kDa/21kDa/23kDa/33kDa
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基因ID
- 5999
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UniProt
- P49798
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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