RASD1 抗体 (AA 132-281)
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北京 101111
Quick Overview for RASD1 抗体 (AA 132-281) (ABIN7269879)
抗原
See all RASD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 132-281
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原理
- RASD1 Rabbit pAb
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序列
- TKENVDVPLV ICGNKGDRDF YREVDQREIE QLVGDDPQRC AYFEISAKKN SSLDQMFRAL FAMAKLPSEM SPDLHRKVSV QYCDVLHKKA LRNKKLLRAG SGGGGGDPGD AFGIVAPFAR RPSVHSDLMY IREKASAGSQ AKDKERCVIS
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))
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别名
- RASD1
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背景
- This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RASD1,AGS1,DEXRAS1,MGC:26290,Signal Transduction,G protein signaling,Signal Transduction,RASD1
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分子量
- 13kDa/31kDa
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基因ID
- 51655
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UniProt
- Q9Y272
抗原
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