Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) 抗体
This 兔 单克隆 antibody specifically detects Ras-Related C3 Botulinum Toxin Substrate 1 in WB. It exhibits reactivity toward 人.
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产品编号 ABIN7269877
发货至:
中国
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Quick Overview for Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) 抗体 (ABIN7269877)
抗原
Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)
适用
人
宿主
兔
克隆类型
单克隆
应用范围
Western Blotting (WB)
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抗原表位
- pSer71
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原理
- Phospho-Rac1/Cdc42-S71 Rabbit mAb
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交叉反应
- 人
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)
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别名
- CDC42/RAC1
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背景
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013],CDC42Hs, G25K, TKS,CDC42/RAC1
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分子量
- 24kDa
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基因ID
- 998, 5879
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UniProt
- P60953, P63000
抗原
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