RASAL1 抗体 (AA 120-340)
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北京 101111
Quick Overview for RASAL1 抗体 (AA 120-340) (ABIN7269873)
抗原
See all RASAL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-340
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原理
- RASAL1 Rabbit pAb
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序列
- ICLSVQMLED GQGRCLRCHV LQARDLAPRD ISGTSDPFAR VFWGSQSLET STIKKTRFPH WDEVLELREM PGAPSPLRVE LWDWDMVGKN DFLGMVEFSP KTLQQKPPKG WFRLLPFPRA EEDSGGNLGA LRVKVRLIED RVLPSQCYQP LMELLMESVQ GPAEEDTASP LALLEELTLG DCRQDLATKL VKLFLGRGLA GRFLDYLTRR EVARTMDPNT L
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human RASAL1 (NP_004649.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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别名
- RASAL1
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背景
- The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described,RASAL1,RASAL,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,RASAL1
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分子量
- 86kDa/90kDa
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基因ID
- 8437
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UniProt
- O95294
抗原
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