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RAB3A 抗体 (AA 100-200)

This anti-RAB3A antibody is a 兔 多克隆 antibody detecting RAB3A in WB 和 IF. Suitable for 人.
产品编号 ABIN7269809
发货至: 中国

Quick Overview for RAB3A 抗体 (AA 100-200) (ABIN7269809)

抗原

See all RAB3A 抗体
RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

适用

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  • 1
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宿主

  • 49
  • 13
  • 3

克隆类型

  • 54
  • 11
多克隆

标记

  • 31
  • 6
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  • 1
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This RAB3A antibody is un-conjugated

应用范围

  • 49
  • 26
  • 14
  • 13
  • 9
  • 7
  • 6
  • 4
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  • 2
  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 10
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    AA 100-200

    原理

    RAB3A Rabbit pAb

    序列

    LMYDITNEES FNAVQDWSTQ IKTYSWDNAQ VLLVGNKCDM EDERVVSSER GRQLADHLGF EFFEASAKDN INVKQTFERL VDVICEKMSE SLDTADPAVT G

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB3A (NP_002857.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

    别名

    RAB3A

    背景

    Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity. Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity. Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By similarity. Stimulates insulin secretion through interaction with RIMS2 or RPH3AL effectors in pancreatic beta cells (By similarity. Regulates calcium-dependent lysosome exocytosis and plasma membrane repair (PMR via the interaction with 2 effectors, SYTL4 and myosin-9/MYH9. Acts as a positive regulator of acrosome content secretion in sperm cells by interacting with RIMS1. Plays also a role in the regulation of dopamine release by interacting with synaptotagmin I/SYT (By similarity. Interacts with MADD (via uDENN domain, the GTP-bound form is preferred for interaction (By similarity.,RAB3A,Signal Transduction,G protein signaling,Signal Transduction,RAB3A

    分子量

    24kDa

    基因ID

    5864

    UniProt

    P20336

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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