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PDHB 抗体

This anti-PDHB antibody is a 兔 单克隆 antibody detecting PDHB in WB 和 IHC. Suitable for 人.
产品编号 ABIN7269772
发货至: 中国

Quick Overview for PDHB 抗体 (ABIN7269772)

抗原

See all PDHB 抗体
PDHB (Pyruvate Dehydrogenase beta (PDHB))

适用

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宿主

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克隆类型

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单克隆

标记

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This PDHB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    PDHB Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Pyruvate Dehydrogenase E1 beta subunit

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PDHB (Pyruvate Dehydrogenase beta (PDHB))

    别名

    PDHB

    背景

    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012],PDHBD, PDHE1-B, PHE1B,Cancer,Carbohydrate metabolism,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,Warburg Effect,PDHB

    分子量

    35kDa

    基因ID

    5162

    UniProt

    P11177

    途径

    Warburg Effect
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