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PDHA1 抗体 (pSer293)

This anti-PDHA1 antibody is a 兔 单克隆 antibody detecting PDHA1 in WB, IF 和 IP. Suitable for 人.
产品编号 ABIN7269768
发货至: 中国

Quick Overview for PDHA1 抗体 (pSer293) (ABIN7269768)

抗原

See all PDHA1 抗体
PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

适用

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宿主

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克隆类型

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单克隆

标记

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This PDHA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

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    pSer293

    原理

    Phospho-PDHA1-S293 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S293 of human PDHA1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

    别名

    PDHA1

    背景

    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],PDHA, PDHAD, PDHCE1A, PHE1A,Cancer,Carbohydrate metabolism,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,Warburg Effect,PDHA1

    分子量

    40kDa

    基因ID

    5160

    UniProt

    P08559

    途径

    Warburg Effect
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