Protein Virilizer Homolog (VIRMA) (AA 1400-1700) 抗体
This 兔 多克隆 antibody specifically detects Protein Virilizer Homolog in WB, IHC 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7269712
发货至:
中国
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Quick Overview for Protein Virilizer Homolog (VIRMA) (AA 1400-1700) 抗体 (ABIN7269712)
抗原
Protein Virilizer Homolog (VIRMA)
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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抗原表位
- AA 1400-1700
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原理
- KIAA1429 Rabbit pAb
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序列
- FMRQILNSDT IGCCGDDNGL MEVEGAHTSR TMSINAAELK QLLQSKEESP ENLFLELEKL VLEHSKDDDN LDSLLDSVVG LKQMLESSGD PLPLSDQDVE PVLSAPESLQ NLFNNRTAYV LADVMDDQLK SMWFTPFQAE EIDTDLDLVK VDLIELSEKC CSDFDLHSEL ERSFLSEPSS PGRTKTTKGF KLGKHKHETF ITSSGKSEYI EPAKRAHVVP PPRGRGRGGF GQGIRPHDIF RQRKQNTSRP PSMHVDDFVA AESKEVVPQD GIPPPKRPLK VSQKISSRGG FSGNRGGRGA F
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human KIAA1429 (NP_056311.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Protein Virilizer Homolog (VIRMA)
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别名
- VIRMA
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背景
- Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA.,KIAA1429,MSTP054,fSAP121,VIRMA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,VIRMA
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分子量
- 128kDa/154kDa/201kDa/202kDa
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基因ID
- 25962
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UniProt
- Q69YN4
抗原
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