Protein Virilizer Homolog (VIRMA) (AA 1400-1700) 抗体
VIRMA
适用: 人
IHC, WB, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Protein Virilizer Homolog (VIRMA)
- 抗原表位
- AA 1400-1700
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
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标记
- 非结合性
- 应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- 原理
- KIAA1429 Rabbit pAb
- 序列
- FMRQILNSDT IGCCGDDNGL MEVEGAHTSR TMSINAAELK QLLQSKEESP ENLFLELEKL VLEHSKDDDN LDSLLDSVVG LKQMLESSGD PLPLSDQDVE PVLSAPESLQ NLFNNRTAYV LADVMDDQLK SMWFTPFQAE EIDTDLDLVK VDLIELSEKC CSDFDLHSEL ERSFLSEPSS PGRTKTTKGF KLGKHKHETF ITSSGKSEYI EPAKRAHVVP PPRGRGRGGF GQGIRPHDIF RQRKQNTSRP PSMHVDDFVA AESKEVVPQD GIPPPKRPLK VSQKISSRGG FSGNRGGRGA F
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human KIAA1429 (NP_056311.2).
- 亚型
- IgG
-
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Protein Virilizer Homolog (VIRMA)
- 别名
- VIRMA
- 背景
- Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA.,KIAA1429,MSTP054,fSAP121,VIRMA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,VIRMA
- 分子量
- 128kDa/154kDa/201kDa/202kDa
- 基因ID
- 25962
- UniProt
- Q69YN4
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