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P4HB 抗体

The 兔 单克隆 anti-P4HB antibody is suitable to detect P4HB in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN7269560
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for P4HB 抗体 (ABIN7269560)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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宿主

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克隆类型

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单克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    P4HB Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human P4HB.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    P4HB

    背景

    This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.,P4HB, CLCRP1, DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, protein disulfide-isomerase,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,Lipid Metabolism,P4HB

    分子量

    57kDa

    基因ID

    5034

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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