PRR5 抗体 (AA 109-388)
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北京 101111
Quick Overview for PRR5 抗体 (AA 109-388) (ABIN7269555)
抗原
See all PRR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 109-388
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原理
- PRR5 Rabbit pAb
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序列
- QKLLDSLAET WDFFFSDVLP MLQAIFYPVQ GKEPSVRQLA LLHFRNAITL SVKLEDALAR AHARVPPAIV QMLLVLQGVH ESRGVTEDYL RLETLVQKVV SPYLGTYGLH SSEGPFTHSC ILEKRLLRRS RSGDVLAKNP VVRSKSYNTP LLNPVQEHEA EGAAAGGTSI RRHSVSEMTS CPEPQGFSDP PGQGPTGTFR SSPAPHSGPC PSRLYPTTQP PEQGLDPTRS SLPRSSPENL VDQILESVDS DSEGIFIDFG RGRGSGMSDL EGSGGRQSVV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 109-388 of human PRR5 (NP_851850.1).
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亚型
- IgG
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anti-Proline Rich 5 (Renal) (PRR5) (C-Term) antibody
PRR5 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (AA 35-84) antibodyPRR5 适用: 人, 马, Cow, 犬, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (N-Term) antibodyPRR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (N-Term) antibodyPRR5 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRR5 (Proline Rich 5 (Renal) (PRR5))
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别名
- PRR5
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背景
- This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.,PRR5,FLJ20185k,PP610,PROTOR-1,PROTOR1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,PRR5
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分子量
- 31kDa/32kDa/41kDa/42kDa/45kDa
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基因ID
- 55615
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UniProt
- P85299
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途径
- PI3K-Akt Signaling
抗原
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