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PRR5 抗体 (AA 109-388)

This anti-PRR5 antibody is a 兔 多克隆 antibody detecting PRR5 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7269555
发货至: 中国

Quick Overview for PRR5 抗体 (AA 109-388) (ABIN7269555)

抗原

See all PRR5 抗体
PRR5 (Proline Rich 5 (Renal) (PRR5))

适用

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宿主

  • 42

克隆类型

  • 42
多克隆

标记

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This PRR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 109-388

    原理

    PRR5 Rabbit pAb

    序列

    QKLLDSLAET WDFFFSDVLP MLQAIFYPVQ GKEPSVRQLA LLHFRNAITL SVKLEDALAR AHARVPPAIV QMLLVLQGVH ESRGVTEDYL RLETLVQKVV SPYLGTYGLH SSEGPFTHSC ILEKRLLRRS RSGDVLAKNP VVRSKSYNTP LLNPVQEHEA EGAAAGGTSI RRHSVSEMTS CPEPQGFSDP PGQGPTGTFR SSPAPHSGPC PSRLYPTTQP PEQGLDPTRS SLPRSSPENL VDQILESVDS DSEGIFIDFG RGRGSGMSDL EGSGGRQSVV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 109-388 of human PRR5 (NP_851850.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PRR5 (Proline Rich 5 (Renal) (PRR5))

    别名

    PRR5

    背景

    This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.,PRR5,FLJ20185k,PP610,PROTOR-1,PROTOR1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,PRR5

    分子量

    31kDa/32kDa/41kDa/42kDa/45kDa

    基因ID

    55615

    UniProt

    P85299

    途径

    PI3K-Akt Signaling
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