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PRNP 抗体 (AA 23-230)

This anti-PRNP antibody is a 兔 多克隆 antibody detecting PRNP in WB 和 IHC. Suitable for 人.
产品编号 ABIN7269516
发货至: 中国

Quick Overview for PRNP 抗体 (AA 23-230) (ABIN7269516)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

  • 94
  • 36
  • 35
  • 13
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 90
  • 20
  • 3
  • 2
  • 1

克隆类型

  • 81
  • 35
多克隆

标记

  • 57
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PRNP antibody is un-conjugated

应用范围

  • 62
  • 35
  • 27
  • 26
  • 24
  • 15
  • 12
  • 11
  • 11
  • 7
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

KO Validated
  • 抗原表位

    • 15
    • 15
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-230

    原理

    [KO Validated] Prion Protein Rabbit pAb

    序列

    KKRPKPGGWN TGGSRYPGQG SPGGNRYPPQ GGGGWGQPHG GGWGQPHGGG WGQPHGGGWG QPHGGGWGQG GGTHSQWNKP SKPKTNMKHM AGAAAAGAVV GGLGGYMLGS AMSRPIIHFG SDYEDRYYRE NMHRYPNQVY YRPMDEYSNQ NNFVHDCVNI TIKQHTVTTT TKGENFTETD VKMMERVVEQ MCITQYERES QAYYQRGS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 23-230 of human Prion Protein (NP_001073592.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRNP

    背景

    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.,PRNP,ASCR,AltPrP,CD230,CJD,GSS,KURU,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,p27-30,Immunology & Inflammation,CD markers,Neuroscience,Neurodegenerative Diseases,Stem Cells,Hematopoietic Progenitors,PRNP

    分子量

    8kDa/26kDa/27kDa

    基因ID

    5621

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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