POF1B 抗体 (AA 330-560)
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北京 101111
Quick Overview for POF1B 抗体 (AA 330-560) (ABIN7269509)
抗原
See all POF1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-560
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原理
- POF1B Rabbit pAb
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序列
- LVLSTFSNIR EELGHLQNDM TSLENDKMRL EKDLSFKDTQ LKEYEELLAS VRANNHQQQQ GLQDSSSKCQ ALEENNLSLR HTLSDMEYRL KELEYCKRNL EQENQNLRMQ VSETCTGPML QAKMDEIGNH YTEMVKNLRM EKDREICRLR SQLNQYHKDV SKREGSCSDF QFKLHELTSL LEEKDSLIKR QSEELSKLRQ EIYSSHNQPS TGGRTTITTK KYRTQYPILG L
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- POF1B (Premature Ovarian Failure, 1B (POF1B))
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别名
- POF1B
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背景
- Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010],POF;POF2B;POF1B,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Microfilaments,POF1B
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基因ID
- 79983
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UniProt
- Q8WVV4
抗原
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