PRDM9 抗体
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- 抗原 See all PRDM9 抗体
- PRDM9 (PR Domain Containing 9 (PRDM9))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM9 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- PRDM9 Rabbit pAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human PRDM9.
- 亚型
- IgG
- Top Product
- Discover our top product PRDM9 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PRDM9 (PR Domain Containing 9 (PRDM9))
- 别名
- PRDM9 (PRDM9 产品)
- 背景
- The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described.,PFM6, KMT8B, MSBP3, ZNF899, MEISETZ,PRDM9
- 分子量
- 103kDa
- 基因ID
- 56979
- UniProt
- Q9NQV7
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