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PCBP1 抗体

This anti-PCBP1 antibody is a 兔 单克隆 antibody detecting PCBP1 in WB. Suitable for 人.
产品编号 ABIN7269448
发货至: 中国
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Quick Overview for PCBP1 抗体 (ABIN7269448)

抗原

See all PCBP1 抗体
PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

适用

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宿主

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克隆类型

  • 31
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单克隆

标记

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This PCBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    hnRNP E1/PCBP1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human hnRNP E1/hnRNP E1/PCBP1.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

    别名

    PCBP1

    背景

    This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.,PCBP1; HEL-S-85; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X; poly(rC)-binding protein 1,Epigenetics & Nuclear Signaling,RNA Binding,,PCBP1

    分子量

    40kDa

    基因ID

    5093

    UniProt

    Q15365
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