PVRL4 抗体 (AA 371-510)
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北京 101111
Quick Overview for PVRL4 抗体 (AA 371-510) (ABIN7269433)
抗原
See all PVRL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 371-510
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原理
- PVRL4 Rabbit pAb
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序列
- MSRYHRRKAQ QMTQKYEEEL TLTRENSIRR LHSHHTDPRS QPEESVGLRA EGHPDSLKDN SSCSVMSEEP EGRSYSTLTT VREIETQTEL LSPGSGRAEE EEDQDEGIKQ AMNHFVQENG TLRAKPTGNG IYINGRGHLV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 371-510 of human PVRL4 (NP_112178.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
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别名
- NECTIN4
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背景
- This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.,NECTIN4,EDSS1,LNIR,PRR4,PVRL4,nectin-4,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,NECTIN4
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分子量
- 24kDa/55kDa
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基因ID
- 81607
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UniProt
- Q96NY8
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途径
- Cell-Cell Junction Organization
抗原
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