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PIM1 抗体

This anti-PIM1 antibody is a 兔 单克隆 antibody detecting PIM1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7269375
发货至: 中国

Quick Overview for PIM1 抗体 (ABIN7269375)

抗原

See all PIM1 抗体
PIM1 (Pim-1 Oncogene (PIM1))

适用

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宿主

  • 98
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克隆类型

  • 89
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单克隆

标记

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This PIM1 antibody is un-conjugated

应用范围

  • 86
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    PIM1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human PIM1.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PIM1 (Pim-1 Oncogene (PIM1))

    别名

    PIM1

    背景

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],PIM,PIM1,PIM1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Chromatin Remodeling,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Phosphorylation,Epigenetics & Nuclear Signaling,Hematopoietic Progenitors,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,Stem Cells,PIM1

    分子量

    35kDa/45kDa

    基因ID

    5292

    UniProt

    P11309

    途径

    Glycosaminoglycan Metabolic Process
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