PIM1 抗体
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北京 101111
Quick Overview for PIM1 抗体 (ABIN7269375)
抗原
See all PIM1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PIM1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human PIM1.
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PIM1 (Pim-1 Oncogene (PIM1))
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别名
- PIM1
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背景
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],PIM,PIM1,PIM1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Chromatin Remodeling,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Phosphorylation,Epigenetics & Nuclear Signaling,Hematopoietic Progenitors,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,Stem Cells,PIM1
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分子量
- 35kDa/45kDa
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基因ID
- 5292
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UniProt
- P11309
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途径
- Glycosaminoglycan Metabolic Process
抗原
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