PLSCR1 抗体
Our Local Distributor
北京 101111
Quick Overview for PLSCR1 抗体 (ABIN7269354)
抗原
See all PLSCR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Phospholipid Scramblase 1 (PLSCR1) Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human Phospholipid Phospholipid Scramblase 1 (PLSCR1) (PLSCR1)
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PLSCR1 (phospholipid Scramblase 1 (PLSCR1))
-
别名
- PLSCR1
-
背景
- Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5 (By similarity. Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A. Negatively regulates FcR-mediated phagocytosis in differentiated macrophages. May contribute to cytokine-regulated cell proliferation and differentiation (By similarity. May play a role in the antiviral response of interferon (IFN by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. Acts as an attachment receptor for HCV.,MMTRA1B,Calcium Signaling,Cardiovascular,Lipids,Lipids_Lipoproteins/Apolipoproteins,Neuroscience,Signal Transduction,PLSCR1
-
分子量
- 35kDa
-
基因ID
- 5359
-
UniProt
- O15162
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-