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C14orf166 抗体 (AA 151-244) (HRP)

This anti-C14orf166 antibody is a 兔 多克隆 antibody detecting C14orf166 in IHC (p), ELISA 和 IHC (fro). Suitable for 人.
产品编号 ABIN717425
发货至: 中国

Quick Overview for C14orf166 抗体 (AA 151-244) (HRP) (ABIN717425)

抗原

See all C14orf166 抗体
C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

适用

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宿主

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克隆类型

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多克隆

标记

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This C14orf166 antibody is conjugated to HRP

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 3
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    • 1
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    AA 151-244

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RLLM1/C14orf166

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

    别名

    RLLM1

    背景

    Synonyms: CGI 99, CGI99, CLE, Homeobox prox 1, RLLM1, Chromosome 14 open reading frame 166, CLE7, LCRP369, RLL mot containing 1, CN166_HUMAN.

    Background: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

    基因ID

    51637
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