PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) 抗体
This 兔 单克隆 antibody specifically detects PAK4/PAK5/PAK6 in WB. It exhibits reactivity toward 人.
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产品编号 ABIN7269163
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) 抗体 (ABIN7269163)
抗原
PAK4/PAK5/PAK6
适用
人
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB)
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抗原表位
- pSer474, pSer560, pSer602
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原理
- Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding S474 of human PAK4
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亚型
- IgG
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anti-PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) antibody
适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB445 unconjugated Recombinant Antibody
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PAK4/PAK5/PAK6
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背景
- PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],PAK4/PAK5/PAK6
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分子量
- 64, 80, 75 kDa
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基因ID
- 10298, 57144, 56924
抗原
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