PHOX2B 抗体
Quick Overview for PHOX2B 抗体 (ABIN7269159)
抗原
See all PHOX2B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PHOX2B Rabbit mAb
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交叉反应
- 人, 小鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human PHOX2B
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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别名
- PHOX2B
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背景
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016],NBLST2, NBPhox, PMX2B,Epigenetics & Nuclear Signaling,Neuroscience,Signal Transduction,Transcription Factors,PHOX2B
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分子量
- 35kDa
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基因ID
- 8929
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UniProt
- Q99453
抗原
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