ORC1 抗体 (AA 696-856)
Quick Overview for ORC1 抗体 (AA 696-856) (ABIN7269110)
抗原
See all ORC1 (ORC1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 696-856
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原理
- ORC1 Rabbit pAb
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序列
- EDDAIQLVAR KVAALSGDAR RCLDICRRAT EICEFSQQKP DSPGLVTIAH SMEAVDEMFS SSYITAIKNS SVLEQSFLRA ILAEFRRSGL EEATFQQIYS QHVALCRMEG LPYPTMSETM AVCSHLGSCR LLLVEPSRND LLLRVRLNVS QDDVLYALKD E
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 696-856 of human ORC1 (NP_001177748.1).
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亚型
- IgG
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anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibody
ORC1L 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibodyORC1L 适用: 人 WB, IP 宿主: 大鼠 Monoclonal 7A7 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 1-110) antibodyORC1L 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (Internal Region) antibodyORC1L 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 1-110) antibodyORC1L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibodyORC1L 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal 7F6-1 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 170-220) antibodyORC1L 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))
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别名
- ORC1
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背景
- The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ORC1,HSORC1,ORC1L,PARC1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,ORC1
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分子量
- 97kDa
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基因ID
- 4998
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UniProt
- Q13415
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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