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NCAPD2 抗体

The 兔 单克隆 anti-NCAPD2 antibody is suitable to detect NCAPD2 in samples from 人. It has been validated for WB.
产品编号 ABIN7268948
发货至: 中国
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Quick Overview for NCAPD2 抗体 (ABIN7268948)

抗原

See all NCAPD2 抗体
NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

适用

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宿主

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克隆类型

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单克隆

标记

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This NCAPD2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    CNAP1 Rabbit mAb

    交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human CNAP1.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

    别名

    CNAP1

    背景

    Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.,NCAPD2, CAP-D2, CNAP1, hCAP-D2, condensin complex subunit 1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,CNAP1

    分子量

    150kDa

    基因ID

    9918

    UniProt

    Q15021
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