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AMFR 抗体 (AA 85-180)

This anti-AMFR antibody is a 兔 多克隆 antibody detecting AMFR in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN717371
发货至: 中国

Quick Overview for AMFR 抗体 (AA 85-180) (ABIN717371)

抗原

See all AMFR 抗体
AMFR (Autocrine Motility Factor Receptor (AMFR))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This AMFR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 85-180

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human AMFR/RNF45

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    AMFR (Autocrine Motility Factor Receptor (AMFR))

    别名

    RNF45

    背景

    Synonyms: AMF receptor, AMF receptor isoform 1, AMF receptor isoform 2, AMFR, AMFR2_HUMAN, Autocrine motility factor receptor, Autocrine motility factor receptor precursor, isoform 1, Autocrine motility factor receptor precursor, isoform 2, E3 ubiquitin-protein ligase AMFR, gp78, RING finger protein 45, RNF 45, RNF45.

    Background: E3 ubiquitin-protein ligase which can target both itself and other proteins including CD3D and APOB for proteasomal degradation. Mediates polyubiquitination of CYP3A4. Specific receptor for the autocrine motility factor. Mediates tumor invasion and metastasis. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Promotes ubiquitination of misfolded proteins such as mutant CFTR, proposed to mediate sequential ubiquitination by recognizing already ubiquitin-conjugated substrates and to cooperate with E3 ubiquitin-protein ligase RNF5.

    基因ID

    267

    途径

    ER-Nucleus Signaling
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