MBNL1 抗体
Quick Overview for MBNL1 抗体 (ABIN7268704)
抗原
See all MBNL1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MBNL1 Rabbit mAb
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交叉反应
- 人
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human MBNL1
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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别名
- MBNL1
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背景
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015],EXP, MBNL,Epigenetics & Nuclear Signaling,RNA Binding,MBNL1
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分子量
- 40kDa
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基因ID
- 4154
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UniProt
- Q9NR56
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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