MOV10 抗体
Our Local Distributor
北京 101111
Quick Overview for MOV10 抗体 (ABIN7268678)
抗原
See all MOV10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MOV10 Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human MOV10
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MOV10 (Moloney Leukemia Virus 10 (MOV10))
-
别名
- MOV10
-
背景
- 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. Required for microRNA (miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC. Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1 in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity. May function as a messenger ribonucleoprotein (mRNP clearance factor. Exhibits antiviral activity against dengue virus (DENV.,fSAP113, gb110,Epigenetics & Nuclear Signaling,RNA Binding,MOV10
-
分子量
- 114kDa
-
基因ID
- 4343
-
UniProt
- Q9HCE1
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
抗原
-