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- 抗原 See all MLKL 抗体
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This MLKL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- MLKL Rabbit mAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human MLKL.
- 亚型
- IgG
- Top Product
- Discover our top product MLKL Primary Antibody
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anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibody
MLKL 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (Internal Region) antibodyMLKL 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 6E3 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472), (C-Term) antibodyMLKL 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (N-Term) antibodyMLKL 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- 别名
- MLKL (MLKL 产品)
- 背景
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain, however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015],hMLKL,MLKL,Kinase,MLKL
- 分子量
- 54kDa
- 基因ID
- 197259
- UniProt
- Q8NB16
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