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MBD3 抗体

This anti-MBD3 antibody is a 兔 单克隆 antibody detecting MBD3 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7268492
发货至: 中国

Quick Overview for MBD3 抗体 (ABIN7268492)

抗原

See all MBD3 抗体
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

适用

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宿主

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克隆类型

  • 52
  • 14
单克隆

标记

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This MBD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    MBD3 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human MBD3

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    别名

    MBD3

    背景

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],MBD3, methyl-CpG-binding domain protein 3,Epigenetics & Nuclear Signaling,MBD3

    分子量

    33kDa

    基因ID

    53615

    UniProt

    O95983

    途径

    Chromatin Binding
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