MKKS
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
FITC
应用备注
WB,1:200 - 1:2000
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
MKKS
(McKusick-Kaufman Syndrome (MKKS))
别名
MKKS
背景
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.,MKKS,BBS6,HMCS,KMS,MKS,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Immunology & Inflammation,Cytokines,MKKS