MSL1 抗体 (AA 210-300)
This anti-MSL1 antibody is a 兔 多克隆 antibody detecting MSL1 in WB. Suitable for 人.
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Quick Overview for MSL1 抗体 (AA 210-300) (ABIN7268383)
抗原
See all MSL1 抗体
MSL1
(Male-Specific Lethal 1 Homolog (MSL1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This MSL1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 210-300
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原理
- MSL1 Rabbit pAb
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序列
- LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).
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亚型
- IgG
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anti-Male-Specific Lethal 1 Homolog (MSL1) (Middle Region) antibody
MSL1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
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别名
- MSL1
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背景
- Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1
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基因ID
- 339287
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UniProt
- Q68DK7
抗原
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