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MSL1 抗体 (AA 210-300)

This anti-MSL1 antibody is a 兔 多克隆 antibody detecting MSL1 in WB. Suitable for 人.
产品编号 ABIN7268383
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MSL1 抗体 (AA 210-300) (ABIN7268383)

抗原

See all MSL1 抗体
MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

适用

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宿主

  • 14

克隆类型

  • 14
多克隆

标记

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This MSL1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 210-300

    原理

    MSL1 Rabbit pAb

    序列

    LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

    别名

    MSL1

    背景

    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1

    基因ID

    339287

    UniProt

    Q68DK7
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