Lipin 1 抗体
Quick Overview for Lipin 1 抗体 (ABIN7268281)
抗原
See all Lipin 1 (LPIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Lipin 1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Lipin 1
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Lipin 1 (LPIN1)
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别名
- LPIN1
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背景
- This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017],PAP1,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Heart disease,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Diabetes,Heart,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Signal Transduction,LPIN1
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分子量
- 130kDa
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基因ID
- 23175
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UniProt
- Q14693
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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