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LIMD1 抗体 (AA 1-200)

This anti-LIMD1 antibody (ABIN7268259) is a Rabbit Polyclonal antibody detecting LIMD1 in WB. Suitable for Human.
产品编号 ABIN7268259
发货至: 中国

Quick Overview for LIMD1 抗体 (AA 1-200) (ABIN7268259)

抗原

See all LIMD1 抗体
LIMD1 (LIM Domains Containing 1 (LIMD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIMD1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-200

    原理

    LIMD1 Rabbit pAb

    序列

    MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGAGNNPE FEETRRVFAT KMAKIHLQQQ QQQLLQEETL PRGSRGPVNG GGRLGPQARW EVVGSKLTVD GAAKPPLAAS TGAPGAVTTL AAGQPPYPPQ EQRSRPYLHG TRHGSQDCGS RESLATSEMS AFHQPGPCED PSCLTHGDYY DNLSLASPKW GDKPGVSPSI

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human LIMD1 (NP_055055.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    LIMD1 (LIM Domains Containing 1 (LIMD1))

    别名

    LIMD1

    背景

    Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1 and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.,LIMD1,Epigenetics & Nuclear Signaling,LIMD1

    基因ID

    8994

    UniProt

    Q9UGP4

    途径

    Ribonucleoprotein Complex Subunit Organization
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