LIMD1 抗体 (AA 1-200)
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北京 101111
Quick Overview for LIMD1 抗体 (AA 1-200) (ABIN7268259)
抗原
See all LIMD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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原理
- LIMD1 Rabbit pAb
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序列
- MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGAGNNPE FEETRRVFAT KMAKIHLQQQ QQQLLQEETL PRGSRGPVNG GGRLGPQARW EVVGSKLTVD GAAKPPLAAS TGAPGAVTTL AAGQPPYPPQ EQRSRPYLHG TRHGSQDCGS RESLATSEMS AFHQPGPCED PSCLTHGDYY DNLSLASPKW GDKPGVSPSI
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human LIMD1 (NP_055055.1).
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亚型
- IgG
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anti-LIM Domains Containing 1 (LIMD1) (AA 577-674) antibody
LIMD1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-LIM Domains Containing 1 (LIMD1) (C-Term) antibodyLIMD1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domains Containing 1 (LIMD1) (N-Term) antibodyLIMD1 适用: 小鼠, 人, Cow, 豚鼠, 大鼠, Pig, 兔, 斑马鱼, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domains Containing 1 (LIMD1) (N-Term) antibodyLIMD1 适用: 小鼠, 人, Cow, 犬, 豚鼠, 大鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domains Containing 1 (LIMD1) (AA 438-467) antibodyLIMD1 适用: 小鼠, 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domains Containing 1 (LIMD1) (N-Term) antibodyLIMD1 适用: 小鼠, 人, 犬, 大鼠, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domains Containing 1 (LIMD1) (AA 438-467), (C-Term) antibodyLIMD1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32416 unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LIMD1 (LIM Domains Containing 1 (LIMD1))
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别名
- LIMD1
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背景
- Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1 and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.,LIMD1,Epigenetics & Nuclear Signaling,LIMD1
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基因ID
- 8994
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UniProt
- Q9UGP4
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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