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Leptin Receptor 抗体

This anti-Leptin Receptor antibody is a 兔 单克隆 antibody detecting Leptin Receptor in WB 和 IHC. Suitable for 人.
产品编号 ABIN7268210
发货至: 中国

Quick Overview for Leptin Receptor 抗体 (ABIN7268210)

抗原

See all Leptin Receptor (LEPR) 抗体
Leptin Receptor (LEPR)

适用

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宿主

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克隆类型

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单克隆

标记

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This Leptin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    Leptin Receptor Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Leptin Receptor

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Leptin Receptor (LEPR)

    别名

    LEPR

    背景

    The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010],CD295,LEP-R,LEPRD,OB-R,OBR,LEPR,AMPK Signaling Pathway,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Growth factors,Immunology & Inflammation,Lipid Metabolism,Lipids,Lipids_Fatty Acids,Signal Transduction,LEPR

    分子量

    96kDa/102kDa/103kDa/109kDa/132kDa

    基因ID

    3953

    UniProt

    P48357

    途径

    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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