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LGMN 抗体

The 兔 单克隆 anti-LGMN antibody (ABIN7268208) specifically detects LGMN in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7268208
发货至: 中国
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Quick Overview for LGMN 抗体 (ABIN7268208)

抗原

See all LGMN 抗体
LGMN (Legumain (LGMN))

适用

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宿主

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克隆类型

  • 50
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单克隆

标记

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This LGMN antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Legumain (LGMN) Rabbit mAb

    交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Legumain (LGMN) (LGMN)

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    LGMN (Legumain (LGMN))

    别名

    LGMN

    背景

    This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008],AEP, LGMN1, PRSC1,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_Bone,Immunology & Inflammation,Signal Transduction,Ubiquitin,LGMN

    分子量

    36,57kDa

    基因ID

    5641

    UniProt

    Q99538

    途径

    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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