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KSR1 抗体 (AA 320-420)

This anti-KSR1 antibody is a 兔 多克隆 antibody detecting KSR1 in WB 和 IF. Suitable for 人.
产品编号 ABIN7268119
发货至: 中国

Quick Overview for KSR1 抗体 (AA 320-420) (ABIN7268119)

抗原

See all KSR1 抗体
KSR1 (Kinase Suppressor of Ras 1 (KSR1))

适用

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  • 37
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宿主

  • 71
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克隆类型

  • 71
  • 2
多克隆

标记

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This KSR1 antibody is un-conjugated

应用范围

  • 47
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 320-420

    原理

    KSR1 Rabbit pAb

    序列

    SSPAPFPTSS NPSSATTPPN PSPGQRDSRF NFPAAYFIHH RQQFIFPVPS AGHCWKCLLI AESLKENAFN ISAFAHAAPL PEAADGTRLD DQPKADVLEA H

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 320-420 of human KSR1 (NP_055053.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KSR1 (Kinase Suppressor of Ras 1 (KSR1))

    别名

    KSR1

    背景

    Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity. Its kinase activity is unsure (By similarity. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity.,KSR1,KSR,RSU2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-Erk Signaling Pathway,KSR1

    分子量

    84kDa/87kDa/97kDa/102kDa

    基因ID

    8844

    UniProt

    Q8IVT5
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