KAT6B 抗体 (AA 400-500)
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北京 101111
Quick Overview for KAT6B 抗体 (AA 400-500) (ABIN7268062)
抗原
See all KAT6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-500
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原理
- KAT6B Rabbit pAb
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序列
- DLDVFKQAQE LSWEKIECES GVEDCGRYPS VIEFGKYEIQ TWYSSPYPQE YARLPKLYLC EFCLKYMKSK NILLRHSKKC GWFHPPANEI YRRKDLSVFE V
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))
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别名
- KAT6B
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背景
- The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.,KAT6B,GTPTS,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6B
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基因ID
- 23522
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UniProt
- Q8WYB5
抗原
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