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IL4 Receptor 抗体 (AA 26-232)

This anti-IL4 Receptor antibody is a 兔 多克隆 antibody detecting IL4 Receptor in WB 和 IHC. Suitable for 人.
产品编号 ABIN7268001
发货至: 中国

Quick Overview for IL4 Receptor 抗体 (AA 26-232) (ABIN7268001)

抗原

See all IL4 Receptor (IL4R) 抗体
IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

适用

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宿主

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克隆类型

  • 85
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多克隆

标记

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This IL4 Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 26-232

    原理

    IL4R Rabbit pAb

    序列

    MKVLQEPTCV SDYMSISTCE WKMNGPTNCS TELRLLYQLV FLLSEAHTCI PENNGGAGCV CHLLMDDVVS ADNYTLDLWA GQQLLWKGSF KPSEHVKPRA PGNLTVHTNV SDTLLLTWSN PYPPDNYLYN HLTYAVNIWS ENDPADFRIY NVTYLEPSLR IAASTLKSGI SYRARVRAWA QCYNTTWSEW SPSTKWHNSY REPFEQH

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 26-232 of human IL4R (NP_000409.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

    别名

    IL4R

    背景

    This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.,IL4R,CD124,IL-4RA,IL4RA,Cancer,Tumor immunology,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL4R

    分子量

    25kDa/88kDa/89kDa

    基因ID

    3566

    UniProt

    P24394

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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