IFITM2 抗体 (AA 1-100)
Quick Overview for IFITM2 抗体 (AA 1-100) (ABIN7267949)
抗原
See all IFITM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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原理
- IFITM2 Rabbit pAb
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序列
- MNHIVQTFSP VNSGQPPNYE MLKEEQEVAM LGVPHNPAPP MSTVIHIRSE TSVPDHVVWS LFNTLFMNTC CLGFIAFAYS VKSRDRKMVG DVTGAQAYAS
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFITM2 (NP_006426.2).
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亚型
- IgG
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anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-59) antibody
IFITM2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-56) antibodyIFITM2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-132) antibodyIFITM2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-30) antibodyIFITM2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-132) antibodyIFITM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (AA 1-30), (N-Term) antibodyIFITM2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB25534 unconjugated
anti-Interferon Induced Transmembrane Protein 2 (IFITM2) (Internal Region) antibodyIFITM2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))
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别名
- IFITM2
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背景
- IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2, Marburg virus (MARV, Ebola virus (EBOV, Dengue virus (DNV, West Nile virus (WNV, human immunodeficiency virus type 1 (HIV-1, hepatitis C virus (HCV and vesicular stomatitis virus (VSV. Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV and SARS-CoV-2 S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation. IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome.,IFITM2,1-8D,DSPA2c,Cancer,Tumor immunology,Tumor-associated antigens,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,IFITM2
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分子量
- 14kDa
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基因ID
- 10581
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UniProt
- Q01629
抗原
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