ITGA2 抗体
Quick Overview for ITGA2 抗体 (ABIN7267918)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Integrin alpha 2 (ITGA2/CD49b) Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Integrin alpha 2 (ITGA2/CD49b) (ITGA2/CD49b)
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGA2 (Integrin alpha 2 (ITGA2))
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别名
- ITGA2
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背景
- This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],BR,CD49B,GPIa,HPA-5,VLA-2,VLAA2,ITGA2,Cancer,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,ITGA2
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分子量
- 129kDa
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基因ID
- 3673
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UniProt
- P17301
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途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
抗原
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