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INPP5E 抗体 (AA 510-630)

INPP5E 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267883
发货至: 中国
  • 抗原 See all INPP5E 抗体
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    抗原表位
    • 4
    • 3
    • 2
    AA 510-630
    适用
    • 18
    • 10
    • 10
    宿主
    • 16
    • 2
    克隆类型
    • 18
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INPP5E antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    INPP5E Rabbit pAb
    序列
    LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).
    亚型
    IgG
    Top Product
    Discover our top product INPP5E Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    别名
    INPP5E (INPP5E 产品)
    别名
    1200002L24Rik antibody, 72kDa antibody, mKIAA0123 antibody, CORS1 antibody, CPD4 antibody, JBTS1 antibody, MORMS antibody, PPI5PIV antibody, PMPCA antibody, inositol polyphosphate-5-phosphatase E antibody, Inpp5e antibody, INPP5E antibody
    背景
    The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin,INPP5E,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,INPP5E
    分子量
    66kDa/70kDa
    基因ID
    56623
    UniProt
    Q9NRR6
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