INPP5E 抗体 (AA 510-630)
Quick Overview for INPP5E 抗体 (AA 510-630) (ABIN7267883)
抗原
See all INPP5E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-630
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原理
- INPP5E Rabbit pAb
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序列
- LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).
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亚型
- IgG
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anti-Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (C-Term) antibody
INPP5E 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-133) antibodyINPP5E 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-644) antibodyINPP5E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-644) antibodyINPP5E 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (C-Term) antibodyINPP5E 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
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别名
- INPP5E
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背景
- The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin,INPP5E,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,INPP5E
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分子量
- 66kDa/70kDa
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基因ID
- 56623
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UniProt
- Q9NRR6
抗原
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