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Importin 4 抗体 (AA 728-1081)

This anti-Importin 4 antibody is a 兔 多克隆 antibody detecting Importin 4 in WB 和 IF. Suitable for 人.
产品编号 ABIN7267857
发货至: 中国

Quick Overview for Importin 4 抗体 (AA 728-1081) (ABIN7267857)

抗原

See all Importin 4 (IPO4) 抗体
Importin 4 (IPO4)

适用

  • 20
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 22

克隆类型

  • 22
多克隆

标记

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Importin 4 antibody is un-conjugated

应用范围

  • 12
  • 9
  • 7
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 728-1081

    原理

    IPO4 Rabbit pAb

    序列

    LHKACQSCPS EPNTAALQAA LARVVPSYMQ AVNRERERQV VMAVLEALTG VLRSCGTLTL KPPGRLAELC GVLKAVLQRK TACQDTDEEE EEEDDDQAEY DAMLLEHAGE AIPALAAAAG GDSFAPFFAG FLPLLVCKTK QGCTVAEKSF AVGTLAETIQ GLGAASAQFV SRLLPVLLST AQEADPEVRS NAIFGMGVLA EHGGHPAQEH FPKLLGLLFP LLARERHDRV RDNICGALAR LLMASPTRKP EPQVLAALLH ALPLKEDLEE WVTIGRLFSF LYQSSPDQVI DVAPELLRIC SLILADNKIP PDTKAALLLL LTFLAKQHTD SFQAALGSLP VDKAQELQAV LGLS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 728-1081 of human IPO4 (NP_078934.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Importin 4 (IPO4)

    别名

    IPO4

    背景

    Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.,IPO4,Imp4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,IPO4

    分子量

    119kDa

    基因ID

    79711

    UniProt

    Q8TEX9

    途径

    Protein targeting to Nucleus
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