Importin 4 抗体 (AA 728-1081)
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北京 101111
Quick Overview for Importin 4 抗体 (AA 728-1081) (ABIN7267857)
抗原
See all Importin 4 (IPO4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 728-1081
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原理
- IPO4 Rabbit pAb
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序列
- LHKACQSCPS EPNTAALQAA LARVVPSYMQ AVNRERERQV VMAVLEALTG VLRSCGTLTL KPPGRLAELC GVLKAVLQRK TACQDTDEEE EEEDDDQAEY DAMLLEHAGE AIPALAAAAG GDSFAPFFAG FLPLLVCKTK QGCTVAEKSF AVGTLAETIQ GLGAASAQFV SRLLPVLLST AQEADPEVRS NAIFGMGVLA EHGGHPAQEH FPKLLGLLFP LLARERHDRV RDNICGALAR LLMASPTRKP EPQVLAALLH ALPLKEDLEE WVTIGRLFSF LYQSSPDQVI DVAPELLRIC SLILADNKIP PDTKAALLLL LTFLAKQHTD SFQAALGSLP VDKAQELQAV LGLS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 728-1081 of human IPO4 (NP_078934.3).
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亚型
- IgG
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anti-Importin 4 (IPO4) antibody
IPO4 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Importin 4 (IPO4) (Internal Region) antibodyIPO4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Importin 4 (IPO4) antibodyIPO4 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Importin 4 (IPO4) (AA 468-517) antibodyIPO4 适用: 人, 犬, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Importin 4 (IPO4)
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别名
- IPO4
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背景
- Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.,IPO4,Imp4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,IPO4
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分子量
- 119kDa
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基因ID
- 79711
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UniProt
- Q8TEX9
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途径
- Protein targeting to Nucleus
抗原
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