IGHM 抗体
Quick Overview for IGHM 抗体 (ABIN7267845)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Human IgM Rabbit mAb
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交叉反应
- 人
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Human IgM
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亚型
- IgG
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anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 310-452) antibody
IGHM 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 8B9D3 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal IGHM-3776R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB, StM, FACS, IF 宿主: 小鼠 Monoclonal IM373 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 45-178) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 1-489) antibodyIGHM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 兔 Monoclonal IGHM-3135R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal rIGHM-1623 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rIM373 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 103-131) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 391-440) antibodyIGHM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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别名
- IGHM
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背景
- Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes, joining (J) genes, and diversity (D) genes. The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma.,AGM1, MU, VH,Immunology & Inflammation,IGHM
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分子量
- 75kDa
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基因ID
- 3507
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UniProt
- P01871
抗原
-
