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IGHG1 抗体

IGHG1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267844
发货至: 中国
  • 抗原 See all IGHG1 抗体
    IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
    适用
    宿主
    • 34
    • 3
    克隆类型
    • 35
    • 2
    单克隆
    标记
    • 15
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGHG1 antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Human IgG Rabbit mAb
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Human IgG
    亚型
    IgG
    Top Product
    Discover our top product IGHG1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
    别名
    IGHG1 (IGHG1 产品)
    别名
    RGD1359539 antibody, IgG1 antibody, Igh-4 antibody, VH7183 antibody, immunoglobulin heavy constant gamma 1 antibody, immunoglobulin heavy constant gamma 1 (G1m marker) antibody, Ighg1 antibody, IGHG1 antibody
    背景
    As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75 % of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.,Immunology & Inflammation,IGHG1
    分子量
    52kDa
    基因ID
    3500
    UniProt
    P01857, P01859, P01860, P01861
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