HTRA3 抗体 (AA 334-453)
Our Local Distributor
北京 101111
Quick Overview for HTRA3 抗体 (AA 334-453) (ABIN7267790)
抗原
See all HTRA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 334-453
-
原理
- HTRA3 Rabbit pAb
-
序列
- SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
-
别名
- HTRA3
-
背景
- Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.,HTRA3,Prsp,Tasp,Signal Transduction,Neuroscience,Calcium Signaling,HTRA3
-
分子量
- 37kDa/48kDa
-
基因ID
- 94031
-
UniProt
- P83110
抗原
-