HDAC3 抗体
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北京 101111
Quick Overview for HDAC3 抗体 (ABIN7267709)
抗原
See all HDAC3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HDAC3 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human HDAC3.
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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别名
- HDAC3
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背景
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],HD3,RPD3,RPD3-2,HDAC3,Apoptosis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Heart,Heart_Hypertrophy,Immunology & Inflammation,Lipid Metabolism,Lipids,NF-kB Signaling Pathway,Notch Signaling Pathway,Nuclear Receptor Signaling,Signal Transduction,Stem Cells,Tumor suppressors,Wnt/β-Catenin Signaling Pathway,HDAC3
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分子量
- 49kDa
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基因ID
- 8841
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UniProt
- O15379
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途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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