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HDAC3 抗体

This anti-HDAC3 antibody is a 兔 单克隆 antibody detecting HDAC3 in WB 和 IP. Suitable for 人.
产品编号 ABIN7267709
发货至: 中国

Quick Overview for HDAC3 抗体 (ABIN7267709)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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宿主

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克隆类型

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单克隆

标记

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This HDAC3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 原理

    HDAC3 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human HDAC3.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],HD3,RPD3,RPD3-2,HDAC3,Apoptosis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Heart,Heart_Hypertrophy,Immunology & Inflammation,Lipid Metabolism,Lipids,NF-kB Signaling Pathway,Notch Signaling Pathway,Nuclear Receptor Signaling,Signal Transduction,Stem Cells,Tumor suppressors,Wnt/β-Catenin Signaling Pathway,HDAC3

    分子量

    49kDa

    基因ID

    8841

    UniProt

    O15379

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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