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ChT 抗体 (AA 421-580)

This anti-ChT antibody (ABIN7267643) is a Rabbit Polyclonal antibody detecting ChT in WB, IF. Suitable for Human.
产品编号 ABIN7267643
发货至: 中国

Quick Overview for ChT 抗体 (AA 421-580) (ABIN7267643)

抗原

See all ChT 抗体
ChT (High Affinity Choline Transporter (ChT))

适用

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宿主

  • 11
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克隆类型

  • 11
  • 10
多克隆

标记

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This ChT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 421-580

    原理

    SLC5A7 Rabbit pAb

    序列

    LLCVLFVKGT NTYGAVAGYV SGLFLRITGG EPYLYLQPLI FYPGYYPDDN GIYNQKFPFK TLAMVTSFLT NICISYLAKY LFESGTLPPK LDVFDAVVAR HSEENMDKTI LVKNENIKLD ELALVKPRQS MTLSSTFTNK EAFLDVDSSP EGSGTEDNLQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 421-580 of human SLC5A7 (NP_068587.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ChT (High Affinity Choline Transporter (ChT))

    别名

    SLC5A7

    背景

    This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.,SLC5A7,CHT,CHT1,CMS20,HMN7A,Signal Transduction,Endocrine & Metabolism,Neuroscience,SLC5A7

    分子量

    63kDa

    基因ID

    60482

    UniProt

    Q9GZV3
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