GNRHR 抗体 (AA 200-300)
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Quick Overview for GNRHR 抗体 (AA 200-300) (ABIN7267500)
抗原
See all GNRHR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-300
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原理
- GNRHR Rabbit pAb
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序列
- CSFSQWWHQA FYNFFTFSCL FIIPLFIMLI CNAKIIFTLT RVLHQDPHEL QLNQSKNNIP RARLKTLKMT VAFATSFTVC WTPYYVLGIW YWFDPEMLNR L
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GNRHR (NP_000397.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
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别名
- GNRHR
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背景
- This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.,GNRHR,GNRHR1,GRHR,HH7,LHRHR,LRHR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GNRHR
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分子量
- 27kDa/37kDa
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基因ID
- 2798
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UniProt
- P30968
抗原
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