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GSTM1 抗体 (AA 1-181)

GSTM1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267443
发货至: 中国
  • 抗原 See all GSTM1 抗体
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    抗原表位
    • 17
    • 11
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-181
    适用
    • 50
    • 34
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 58
    • 13
    • 1
    • 1
    克隆类型
    • 60
    • 12
    多克隆
    标记
    • 40
    • 13
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This GSTM1 antibody is un-conjugated
    应用范围
    • 59
    • 33
    • 31
    • 12
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    GSTM1 Rabbit pAb
    序列
    MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQTMDNHMQ LGMICYNPEF EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG NKGLEKISAY MKSSRFLPRP VFSKMAVWGN K
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human GSTM1 (NP_666533.1).
    亚型
    IgG
    Top Product
    Discover our top product GSTM1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    别名
    GSTM1 (GSTM1 产品)
    别名
    GST1 antibody, GSTM1-1 antibody, GSTM1a-1a antibody, GSTM1b-1b antibody, GTH4 antibody, GTM1 antibody, H-B antibody, MU antibody, MU-1 antibody, GSTA3 antibody, Gstb-1 antibody, Gstb1 antibody, gst-mu antibody, gst1 antibody, gstm1 antibody, gstm2 antibody, gth4 antibody, gtm1 antibody, glutathione S-transferase mu 1 antibody, glutathione S-transferase M1 antibody, glutathione S-transferase, mu 1 antibody, glutathione S-transferase Mu 1 antibody, glutathione S-transferase mu 2 (muscle) antibody, glutathione S-transferase mu 1 L homeolog antibody, GSTM1 antibody, Gstm1 antibody, LOC100356307 antibody, GSTM2 antibody, LOC100731426 antibody, gstm1.L antibody
    背景
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008],GST1;GSTM1-1;GSTM1a-1a;GSTM1b-1b;GTH4;GTM1;H-B;MU;MU-1;GSTM1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,GSTM1
    分子量
    21kDa/25kDa
    基因ID
    2944
    UniProt
    P09488
    途径
    Negative Regulation of Transporter Activity
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