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GLUD1 抗体

This anti-GLUD1 antibody is a 兔 单克隆 antibody detecting GLUD1 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7267411
发货至: 中国

Quick Overview for GLUD1 抗体 (ABIN7267411)

抗原

See all GLUD1 抗体
GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

适用

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宿主

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克隆类型

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单克隆

标记

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This GLUD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    GLUD1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human GLUD1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

    别名

    GLUD1

    背景

    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016],GDH, GDH1, GLUD,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Signal Transduction,GLUD1

    分子量

    50kDa

    基因ID

    2746

    UniProt

    P00367

    途径

    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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