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GALR2 抗体 (AA 50-150)

This anti-GALR2 antibody is a 兔 多克隆 antibody detecting GALR2 in WB. Suitable for 人.
产品编号 ABIN7267335
发货至: 中国

Quick Overview for GALR2 抗体 (AA 50-150) (ABIN7267335)

抗原

See all GALR2 抗体
GALR2 (Galanin Receptor 2 (GALR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This GALR2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 50-150

    原理

    GALR2 Rabbit pAb

    序列

    LLRGGQAVST TNLFILNLGV ADLCFILCCV PFQATIYTLD GWVFGSLLCK AVHFLIFLTM HASSFTLAAV SLDRYLAIRY PLHSRELRTP RNALAAIGLI W

    交叉反应

    小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GALR2 (NP_003848.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GALR2 (Galanin Receptor 2 (GALR2))

    别名

    GALR2

    背景

    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008],GAL2-R,GALNR2,GALR-2,GALR2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GALR2

    基因ID

    8811

    UniProt

    O43603

    途径

    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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